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Thursday, 22 September 2022

Cancer Risk: Increased risk of cancer in people below 50 years of age worldwide, know what is the reason

 Cancer Risk: Increased risk of cancer in people below 50 years of age worldwide, know what is the reason

Cancer Risk: We know what we should do to reduce our risk of getting cancer, right? Use SPF, don't smoke, avoid processed foods, stay fit, lose weight and get enough sleep. But what if most of the causes of cancer had already affected us in the early years of our life, or worse, had already developed in our body before we were born. A recent study by 'Brigham and Women's Hospital and Harvard University' says that this may happen, especially in cases of cancer that occur before the age of 50 (early cancer). The most important finding in this study, published in Nature Reviews Clinical Oncology, is that people born after 1990 are, for example, more likely to develop cancer before the age of 50 than those born in 1970. 

Youth need to change lifestyle

This means that the risk of it will be higher in younger people than in previous generations. The things we are exposed to early in life can affect our risk of developing cancer later in life, and this review of cancer trends also suggests that these factors may contribute to early cancer. how can be affected. What causes exposure to these factors in early life is still not entirely clear, but the most important factors include diet, lifestyle, environment, and the insects that live in our gut (microbiome). By studying a large number of people, researchers may be able to discover that dietary and lifestyle habits are formed early in life. 

protect yourself from obesity

This is seen in obesity where obese children are more likely to become obese adults. Since obesity is a known risk factor for cancer, it follows that childhood obesity is more likely to develop cancer at a younger age, possibly because they have been exposed to the risk factor for a longer period of time. . Of course, some of these early cancers are detected through better screening programs and early diagnosis, increasing the number of new cancers diagnosed annually worldwide. But that is not the whole story. Early-onset cancers have different genetic characteristics than late-onset cancers and are therefore more likely to spread than cancers diagnosed later in life. 

14 types of cancer studied

This means that those cancers may require a variety of treatments and a more individualized approach that is linked to the age of the patient at the time the cancer develops. The Brigham Study of Gut Bacteria studied 14 types of cancer and found that the genetic structure of cancer and the aggressiveness and growth of cancer were different in patients who developed cancer after age 50 than in those who developed cancer after age 50. It was developed earlier. It appears to be more prominent in several types of bowel cancer (colorectal, pancreatic, stomach). One possible reason for this is related to our diet and microbiome. Gut bacteria are altered by a sugary diet, antibiotics, and breastfeeding. And just as the patterns of these things in society change over time, so do the bacteria in our gut. 

breast cancer risk 

This may justify the implementation of sugar taxes recommended by the World Health Organization. If our healthy cells develop in the womb, the cells that cause cancer may develop at the same time. Maternal diet, obesity and environmental exposures such as air pollution and pesticides are known to increase the risk of chronic diseases and cancer. Conversely, having less food during pregnancy, as seen in famine, increases the risk of breast cancer in the offspring. These two findings will have different implications for societal approaches to reducing cancer risk.

Increased risk of incurable blood cancer among youth

As a hematologist, I care for patients with multiple melanoma, an incurable blood cancer that usually affects people over the age of 70. In recent years, there has been an increase in the number of young people diagnosed with this cancer around the world. This study characterizes obesity as an important risk factor for early disease, but clearly, other risk factors have not yet been uncovered. Understanding what causes early life cancers, which risks really matter and what can be done to prevent them are some of the first steps in developing prevention strategies for future generations. 

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